Metabolic Engineering of Yeast for Xylose Uptake and Fermentation
نویسندگان
چکیده
Fuel ethanol production from plant biomass hydrolysates by the baker’s yeast Saccharomyces cerevisiae is of great economic and environmental significance. Costeffective production of ethanol from plant biomass should not only be based on the readily fermentable starch and sucrose fractions of plant carbohydrates, but also on the much more resistant lignocellulosic fractions. The utilization of xylose, the second abundant monosaccharide in lignocelluloses, is essential for the efficient bioconversion of lignocellulosic fractions of biomass, yet still a technical barrier to the commercial fermentation and a major challenge in metabolic engineering.
منابع مشابه
Yeast metabolic engineering for hemicellulosic ethanol production.
Efficient fermentation of hemicellulosic sugars is critical for the bioconversion of lignocellulosics to ethanol. Efficient sugar uptake through the heterologous expression of yeast and fungal xylose/glucose transporters can improve fermentation if other metabolic steps are not rate limiting. Rectification of cofactor imbalances through heterologous expression of fungal xylose isomerase or modi...
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